Fermentation technology ebooks
For example, even in the presence of abundant oxygen, yeast cells greatly prefer fermentation to aerobic respiration, as long as sugars are readily available for consumption a phenomenon known as the Crabtree effect. The antibiotic activity of hops also inhibits aerobic metabolism in yeast. The development of recombinant DNA techniques over the last 20 years has greatly expanded the opportunities for using microorganisms to produce a broad range of valuable substances. In Microbial Processes and Products, outstanding leaders in using microorganisms as cell factories describe in detail their best laboratory procedures for many processes and products mediated by microorganisms.
An overview chapter describes how to develop strain improvement programs and strategies to optimize fermentation processes. Taking advantage of the most recent developments in such processes, the authors offer step-by-step experimental methods for the optimal design of microbial metabolite production, including semisynthetic derivatives of cephalosporins, erythromycin, antitumor compounds, plasmids for gene therapy and DNA vaccination, L-lysine, vitamins B2 and B12, the sweet-tasting protein thaumatin, the carotenoids b-carotene and astaxanthin, the polysaccharide gellan, and bacteria-producing bacteria for sausage fermentation.
Additionally, the use of phenylacetyl-CoA catabolon for enzymatic synthesis of penicillins, aromatic biotransformations, synthesis of new bioplastics, biosensor design, or synthesis of drug vehicles, and the development of a phosphate encoding gene as a reporter and to monitor gene expression are illustrated. The diverse chemicals and biochemicals produced can be used in human health, nutrition, and environmental protection.
Additional chapters offer techniques for analysis of antimicrobial metabolites and carotenoids, volatile sulfur compounds, metabolic pathway fluxes, gene expression arrays, proteome analysis, bacterial modulation of the innate immune response, bioleaching activity, and heavy metal remediation. Finally, three overview chapters on transport of biological material, deposit of biological material for patent purposes, and protection of biotechnological inventions are shown.
The protocols follow the successful Methods in BiotechnologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
A companion volume, Microbial Enzymes and Biotransformations, describes in detail cutting-edge techniques for the screening, evolution, production, immobilization, and use of enzymes. Wide-ranging and practical, Microbial Processes and Products offers laboratory and industrial scientists a wealth of readily reproducible techniques for the successful microbial generation of biochemical products to serve the needs of human health, nutrition, and environmental protection.
Over the period of last two decades, there has been significant resurgence in solid-state fermentation due to the numerous benefits it offers, especially in the engineering and environmental aspects. SSF has shown much promise in the development of several bioprocesses and products. This resurgence gained further momentum during the last years with the developments in fundamental and applied aspects.
A good deal of information has been generated in published literature and patented information. Several commercial ventures have come up based on SSF in different parts of the world. The contents are organized into four parts: Part 1 deals with the General and Fundamentals aspects of SSF; Part 2 deals with the production of bulk chemicals and products such as enzymes, organic acids, spores and mushrooms in SSF; Part 3 is on the use of SSF for specialty chemicals such as gibberellic acid, antibiotics and other pharmaceutically valuable secondary metabolites, pigments, and aroma compounds; Part 4 deals with the use of SSF miscellaneous application such as SSF for food and feed applications, agro-industrial residues as substrates in SSF and the production of silage and vermicompost.
Surveys the state-of-the-art in industrial fermentation monitoring and control. The main aim of the report is to encourage industry to take up methodologies suggested by research. It draws its conclusions from a one-year study into issues such as: improving data analysis procedures and monitoring techniques; applying estimation methods to enhance on-line information; easing the task of establishing effective closed-loop control systems; utilizing artificial intelligence techniques to improve process fault detection and diagnosis and provide general operator assistance; using optimization approaches where possible to enhance bioprocess profitability from development laboratory scale to large-scale production.
Microbial Technology: Fermentation Technology, Second Edition is a collection of papers that deals with fermentations and modifications of plant or animal products for foods, beverages, and feeds. The papers also review microbial technology: general principles, culture selection, laboratory methods, instrumentation, computer control, product isolation, immobilized cell usage, economics, and microbial patents. Several papers explain the process of fermentation and food modification in cheese, soy sauce, vinegar, mushroom, inocula for blue-veined cheeses, and blue cheese flavor.
One paper discusses the technology of isolation, production, and application of microbial cultures which are commercially available or imminent as inocula for the treatment of wastes, The paper describes these cultures in terms of product characteristics, types of cultures, and application guidelines for waste treatment.
Another paper outlines the procedures used by investigators involved in microbial reaction engineering, as follows: 1 identification of main products and substrates: 2 stoichiometry of the process; 3 kinetics and process rate; and 4 reactor design.
One paper cites examples of immobilized cell systems utilized to prepare fine chemicals, such as the research of Chibata et al. The collection is suitable for food technologists, bio-chemists, cellular biologists, micro-biologists, and scientists involved in food production, medicine, agriculture, and environmental control.
This state-of-the-art volume represents the first comprehensively written book which focuses on the new field of biosorption. This fascinating work conveys essential fundamental information and outlines the perspectives of biosorption. It summarizes the metal-sorbing properties of nonliving bacterial, fungal, and algal biomass, plus highlights relevant metal-binding mechanisms. This volume also discusses the aspects of obtaining and processing microbial biomass and metal-chelating chemicals into industrially applicable biosorbent products.
Microbiologists, chemists, and engineers with an interest in new technological and scientific horizons will find this reference indispensable. Richard Fox Chairman, Scientific Programme Committee Between 25th and 29th September, , people who either apply or research the use of computers in fermentation gathered together at Robinson College, Cambridge, UK. They came from 30 countries. The conference brought together two traditions. Secondly, it brought the expertise of the many members of the International Federation of Automatic Control IFAC , who focused their attention on biotechnology at Noordwijkerhout in the Netherlands in December, Classical strain improvement by recombination.
Medium engineering and metabolic engineering. Fermentation media formulation. Raw materials for fermentation media. Introduction to industrial sterilization. Sterilization of fermentation media and fermented. Air sterilization. Inoculums development. Industrial fermenter design. Measurement and control of bioprocess parameters. Aeration and agitation. Fluid rheology.
Foam formation and its control. Computer applications in fermentation technology. Scale up. Selected bibliography. Downstream Fermentation Technology Preface. Down stream processing I solid liquid separation.
Down stream processing II disintegration methods. Down stream processing III concentration methods. Down stream processing IV purification by chromatography. Down stream processing V product formulation.
Microbiological assays. Key recommendations from the Precision Fermentation science team at each major step of fermentation — "Day zero" i. Key findings that can help you solve problems and improve your results. Download the Free eBook.
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